Baked Mostaccioli
This is the kind of recipe that transforms you from “I can barely boil water” to “Yes, I made this masterpiece from scratch” in about an hour and fifteen minutes.

Picture layers of perfectly cooked pasta swimming in a rich, creamy meat sauce that’s been simmering away while you pretend to have your life together.

The aroma alone will have your neighbors suddenly remembering they need to borrow something right around dinnertime.

We’re talking about golden, bubbly mozzarella on top, a sauce that’s equal parts comfort and sophistication, and pasta that holds its shape like it went to finishing school.

This isn’t just dinner – it’s the kind of meal that makes people ask for the recipe while they’re still chewing.

Best part? It’s basically foolproof, freezer-friendly, and impressive enough to serve to people you actually want to impress.

Ingredients
For the Pasta
- 12 ounces mostaccioli or penne pasta
- Salt for pasta water
For the Meat Sauce
- 1 pound lean ground beef
- 1 large yellow onion, diced
- 3 cloves garlic, minced
- 28 ounces marinara sauce
- 14 ounces canned diced tomatoes with juices
- ½ cup water
- 1½ teaspoons Italian seasoning
- 1 teaspoon granulated sugar
- 1 cup heavy whipping cream
For the Cheese Topping
- 2 cups shredded mozzarella cheese (about 8 oz)
- ¼ cup shredded Parmesan cheese

Instructions
Preparation
- 1 Preheat your oven to 375°F (190°C) and generously grease a 9×13 inch baking dish with butter or cooking spray. This prevents sticking and makes cleanup infinitely easier.
- 2 Cook the mostaccioli pasta according to package directions in well-salted water until al dente – this typically takes 8-10 minutes. The pasta will continue cooking in the oven, so slightly undercooking at this stage prevents mushy results. Drain thoroughly and set aside.
Building the Sauce
- 3 While the pasta cooks, heat a large saucepan or cast iron skillet over medium-high heat. Add the ground beef, diced onion, and minced garlic. Brown the mixture for 6-8 minutes, breaking up the meat with a wooden spoon until no pink remains and the onions are translucent.
- 4 Drain any excess fat from the pan, leaving just enough to keep the mixture moist. Add the marinara sauce, diced tomatoes with their juices, water, Italian seasoning, and sugar. The sugar balances the acidity of the tomatoes – trust the process here.
- 5 Bring the mixture to a gentle simmer and cook uncovered for 5 minutes, stirring occasionally. The sauce should bubble gently around the edges. Add the heavy whipping cream, stir to combine, and simmer for an additional 5 minutes until the sauce has thickened enough to coat the back of a spoon. Taste and season with salt and black pepper as needed.
Assembly and Baking
- 6 Spread 1 cup of the prepared sauce evenly across the bottom of your greased baking dish. This prevents the pasta from sticking and ensures every bite has sauce.
- 7 Layer half of the cooked pasta over the sauce, then top with half of the remaining sauce. Add the remaining pasta in an even layer, then top with all remaining sauce. The layering creates distinct textures and ensures even distribution.
- 8 Sprinkle the mozzarella and Parmesan cheeses evenly over the top. For extra golden results, place the dish on the upper rack of your oven.
- 9 Bake for 25-30 minutes until the casserole is heated through and the cheese is golden brown and bubbling around the edges. The internal temperature should reach 165°F (74°C) when tested with an instant-read thermometer.

Recommended Equipment and Kitchen Tools
Essential Tools (for best results):
- Large saucepan or cast iron skillet – Essential for browning the meat and building the sauce. Cast iron retains heat beautifully and creates better browning
- 9×13 inch baking dish – Glass or ceramic works best for even heat distribution and easy monitoring of browning
- Large pot for pasta – At least 6-quart capacity ensures pasta cooks evenly without sticking
- Wooden spoon or silicone spatula – Perfect for breaking up ground beef and stirring sauce without scratching cookware
Helpful Upgrades:
- Instant-read thermometer – Takes the guesswork out of checking doneness and food safety
- Kitchen scale – For precise pasta measurements and consistent results every time
- Fine-mesh strainer – Ensures pasta drains completely, preventing watery casseroles
- Aluminum foil – Essential for make-ahead preparation and freezer storage
Nice-to-Have Options:
- Stand mixer with paddle attachment – If you’re shredding your own cheese, this makes quick work of it
- Food processor – Perfect for quickly dicing onions and mincing garlic uniformly
- Bench scraper – Helpful for transferring ingredients and keeping your workspace organized

Recipe Variations and Dietary Modifications
Protein Variations:
- Italian sausage – Replace ground beef with sweet or spicy Italian sausage for deeper flavor
- Ground turkey – Use 93/7 lean ground turkey for a lighter option, add 1 tablespoon olive oil to prevent drying
- Vegetarian option – Replace meat with 3 cups finely chopped vegetables (bell peppers, zucchini, mushrooms, eggplant) sautéed until tender
Pasta Alternatives:
- Gluten-free pasta – Use your favorite gluten-free penne or mostaccioli, cook 1-2 minutes less than package directions
- Whole wheat pasta – Adds fiber and nutty flavor, may need 2-3 extra minutes cooking time
- Protein pasta – Made from lentils or chickpeas for extra protein and different texture
Cheese Variations:
- Italian blend – Mix mozzarella with provolone and Romano for complex flavor
- Dairy-free option – Use plant-based mozzarella and nutritional yeast instead of Parmesan
- Extra indulgent – Add ½ cup ricotta cheese dolloped throughout layers
Flavor Enhancements:
- Mediterranean twist – Add ½ cup sun-dried tomatoes and ¼ cup fresh basil
- Spicy version – Include 1 teaspoon red pepper flakes and use spicy marinara
- Herb-forward – Add 2 tablespoons fresh oregano and ¼ cup fresh parsley

Nutritional Information and Health Benefits
Key Nutritional Highlights:
Each serving of this baked mostaccioli provides approximately 485 calories with a balanced macronutrient profile. The combination of lean ground beef and pasta delivers 28 grams of protein per serving, making it an excellent choice for muscle maintenance and satiety. The dish contains 45 grams of carbohydrates, primarily from the pasta and tomatoes, providing sustained energy. The heavy cream and cheese contribute 22 grams of fat, including beneficial calcium and vitamin A.
Health Benefits of Main Ingredients:
The lean ground beef provides high-quality complete protein plus essential B vitamins, particularly B12 for nerve function and iron for oxygen transport. Tomatoes in the marinara sauce and diced tomatoes are rich in lycopene, a powerful antioxidant that becomes more bioavailable when cooked. The onions and garlic offer anti-inflammatory compounds and prebiotics that support digestive health. Mozzarella cheese contributes significant calcium for bone health and protein for muscle maintenance.
Dietary Considerations:
This recipe contains gluten from wheat pasta and dairy from cheese and cream. It’s naturally nut-free and can be adapted for various dietary needs. The dish provides approximately 15% of daily calcium needs and 25% of daily protein requirements. For balanced nutrition, pair with a green salad or steamed vegetables to increase fiber and micronutrient content.

Smart Swaps and Ingredient Substitutions
Common Substitutions:
- Heavy cream → Half-and-half or whole milk (reduce by ¼ cup to prevent thinning)
- Ground beef → Ground turkey, chicken, or plant-based crumbles (adjust cooking time as needed)
- Marinara sauce → Crushed tomatoes plus 1 teaspoon each dried basil and oregano
- Fresh garlic → 1 teaspoon garlic powder (add with other seasonings)
Budget-Friendly Swaps:
- Mozzarella cheese → Italian cheese blend or sharp cheddar for similar melting properties
- Heavy cream → ¾ cup whole milk plus ¼ cup butter for richness
- Canned diced tomatoes → 2 large fresh tomatoes, diced (drain excess liquid)
Pantry Emergency Substitutions:
- Italian seasoning → ½ teaspoon each dried basil, oregano, and thyme
- Mostaccioli pasta → Penne, rigatoni, or any tube-shaped pasta
- Yellow onion → 2 tablespoons onion powder mixed into sauce
- Parmesan cheese → 2 tablespoons nutritional yeast for umami flavor
Pro Tips for Substitutions:
- When using milk instead of cream, add 1 tablespoon flour to prevent curdling
- Ground turkey needs extra seasoning – add ½ teaspoon extra Italian seasoning
- Fresh herbs should be added in the last 5 minutes of cooking to preserve flavor

Make It Diabetes-Friendly
Carb Reduction Strategies:
- Replace regular pasta with shirataki noodles or zucchini noodles to reduce carbs by 75%
- Use whole wheat pasta to increase fiber content, which slows sugar absorption
- Reduce pasta portion to 8 ounces instead of 12, add 2 cups diced vegetables like bell peppers and zucchini
Dairy Modifications:
- Substitute heavy cream with ¾ cup unsweetened almond milk plus 2 tablespoons cream cheese for creaminess with fewer carbs
- Choose part-skim mozzarella to reduce saturated fat while maintaining protein content
- Add Greek yogurt – ¼ cup plain Greek yogurt stirred in at the end adds protein and probiotics
Sugar and Sodium Adjustments:
- Eliminate added sugar – the natural sugars in tomatoes provide sufficient sweetness
- Choose no-sugar-added marinara sauce to control carb content
- Use low-sodium diced tomatoes and season with herbs instead of salt
Portion and Pairing Tips:
- Serve smaller portions (1 cup instead of 1.5 cups) paired with a large green salad
- Estimated carbs per modified serving: 25-30 grams versus 45 grams in original
- Add lean protein like grilled chicken to increase satiety without adding carbs
Total Carb Reduction: Modified version contains approximately 35% fewer carbohydrates than the original recipe.

Perfect Pairing Suggestions
Beverage Pairings:
A medium-bodied red wine like Chianti or Sangiovese complements the rich tomato sauce beautifully, while the acidity cuts through the creamy elements. For beer lovers, a crisp lager or wheat beer provides a refreshing contrast to the hearty casserole. Non-alcoholic options include sparkling water with lemon or a robust iced tea with herbs like basil or oregano that echo the Italian flavors.
Side Dish Recommendations:
A crisp Caesar salad with homemade croutons provides textural contrast and fresh flavors that cleanse the palate between bites. Roasted vegetables like zucchini, bell peppers, or broccoli add color and nutrients while complementing the Italian flavor profile. Garlic bread or focaccia rounds out the meal for heartier appetites, while steamed green beans with almonds offer a lighter accompaniment.
Complete Meal Ideas:
Start with antipasto featuring olives, fresh mozzarella, and cured meats to build anticipation. The baked mostaccioli serves as a satisfying main course that needs little accompaniment beyond a simple green salad. Finish with a light dessert like lemon sorbet or tiramisu to complete the Italian theme without overwhelming the palate.
Occasion Suggestions:
This recipe shines at family gatherings, potluck dinners, and casual entertaining where comfort food is welcome. It’s perfect for Sunday dinners, holiday meals, or any time you want to feed a crowd without stress. The make-ahead nature makes it ideal for busy weeknights or when hosting guests.

Pro Tips and Troubleshooting
Professional Techniques:
Salt your pasta water generously – it should taste like seawater. This is your only chance to season the pasta itself. When browning the ground beef, resist the urge to stir constantly; let it develop a good sear for deeper flavor. Always taste your sauce before assembly and adjust seasoning accordingly – the flavors will concentrate slightly during baking.
Common Mistakes and Solutions:
Overcooking the pasta initially leads to mushy results after baking. Cook it 1-2 minutes less than package directions. If your sauce seems too thin, simmer it uncovered for a few extra minutes before adding the cream. Watery casseroles usually result from not draining pasta thoroughly or using too much liquid in the sauce.
Storage and Reheating:
Store leftovers covered in the refrigerator for up to 4 days. Reheat individual portions in the microwave at 50% power to prevent the cheese from becoming rubbery. For larger portions, cover with foil and reheat in a 325°F (163°C) oven for 15-20 minutes until heated through.
Make-Ahead Strategy:
Assemble the entire casserole up to 2 days ahead, cover tightly with plastic wrap, and refrigerate. Add 10-15 minutes to the baking time when cooking from cold. For freezing, wrap assembled casserole in plastic wrap and aluminum foil for up to 3 months. Thaw overnight before baking as directed.

This baked mostaccioli proves that sometimes the best recipes are the ones that make you look like a culinary genius while requiring nothing more than following directions and not burning anything. It’s comfort food that comforts everyone – the cook included.